Antibodies from Llama helps world medicine in fight against the Coronavirus

Grippe et vaccin Sciences et Avenir

The antibodies produced by the Llama could be used against COVID-19.


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A study by the University of Texas, USA, led to the discovery of antibodies that can "bind" to one of the key proteins on the surface of the coronavirus. The researchers explain that these antibodies attach to those proteins that allow SARS-CoV-2 to infect cells in the host organism. In addition to this discovery with significant potential against the pandemic we are going through, scientists also point to the unusual source from which they obtained these antibodies: a blade called Winter, notes Neuroscience News.

Antibodies for medicine génération et ingénierie MI-mAbs

This is one of the first known antibodies that can neutralize SARS-CoV-2, said Jason McLellan, a member of the University of Texas Department of Molecular Bioscience and co-author of the study.

The effectiveness of these antibodies, called VHH-72, has been proven in laboratory cultures, and researchers are now focusing on studying their effects in laboratory animals. If these tests prove conclusive then scientists could receive the necessary approvals to start human testing.

Single-Antibodies Fusion explained Free Full-Text MDPI

"Vaccines should be given a month or two before infection to provide protection," said Dr. McLellan. "In the case of antibody therapies, we administer protective antibodies directly to a patient and thus, immediately after treatment, they should be protected. Antibodies could also be used to treat someone who is already ill to reduce the severity of the disease, ” he added.

Structural Basis for Potent Neutralization of Betacoronaviruses ScienceDirect.com

Scientists explain that when faced with an infection, the immune system of the lamellae produces two types of antibodies: one of them is similar to those produced by the human immune system and a type of small antibody, VHH- 72. The latter have only a quarter of the former and, in theory, could be administered with an inhaler. Scientists believe that such a method of administration could be extremely effective because it "directly" attacks the site of infection.



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The study was published in Cell.