Showing posts with label chemistry. Show all posts
Showing posts with label chemistry. Show all posts

Tuesday, January 31, 2017

Researchers are close to discover the factor that determined the evolution of life on Earth

Credit: klss/Shutter Stock
Modern science has advanced significantly over the last couple of decades. We’ve managed to answer several of the world’s most long-standing questions, but some answers have continued to elude today’s scientists, including how life first emerged from Earth’s primordial soup.

However, a collaboration of physicists and biologists in Germany may have just found an explanation to how living cells first evolved.

In 1924, Russian biochemist Alexander Oparin proposed the idea that the first living cells could have evolved from liquid droplet protocells.

He believed these protocells could have acted as naturally forming, membrane-free containers that concentrated chemicals and fostered reactions.

Aleksandr Oparin (right) and Andrei Kursanov in the enzymology laboratory, 1938 Credit: wikipedia

In their hunt for the origin of life, a team of scientists from the Max Planck Institute for the Physics of Complex Systems and the Institute of Molecular Cell Biology and Genetics, both in Dresden, drew from Oparin’s hypothesis by studying the physics of 'chemically active' droplets (droplets that cycle molecules from the fluid in which they are surrounded).

Unlike a 'passive' type of droplet - like oil in water, which will just continue to grow as more oil is added to the mix - the researchers realised that chemically active droplets grow to a set size and then divide on their own accord.

This behaviour mimics the division of living cells and could, therefore, be the link between the nonliving primordial liquid soup from which life sprung and the living cells that eventually evolved to create all life on Earth.

"It makes it more plausible that there could have been a spontaneous emergence of life from nonliving soup," said Frank Jülicher, co-author of the study that appeared in the journal Nature Physics in December.

It’s an explanation of "how cells made daughters," said lead researcher David Zwicker. "This is, of course, key if you want to think about evolution."


Add a droplet of life

Some have speculated that these proto-cellular droplets might still be inside our system "like flies in life’s evolving amber".

To explore that hypothesis, the team studied the physics of centrosomes, which are organelles active in animal cell division that seem to behave like droplets.

Zwicker modelled an 'out-of-equilibrium' centrosome system that was chemically active and cycling constituent proteins continuously in and out of the surrounding liquid cytoplasm.

The proteins behave as either soluble (state A) or insoluble (state B).  An energy source can trigger a state reversal, causing the protein in state A to transform into state B by overcoming a chemical barrier. 

As long as there was an energy source, this chemical reaction could happen.

"In the context of early Earth, sunlight would be the driving force," Jülicher said.

Odarin famously believed that lighting strikes or geothermal activity on early Earth could’ve triggered these chemical reactions from the liquid protocells.

This constant chemical influx and efflux would only counterbalance itself, according to Zwicker, when a certain volume was reached by the active droplet, which would then stop growing.

Typically, the droplets could grow to about tens or hundreds of microns, according to Zwicker’s simulations. That’s about the same scale as cells.

The next step is to identify when these protocells developed the ability to transfer genetic information.

Jülicher and his colleagues believe that somewhere along the way, the cells developed membranes, perhaps from the crusts they naturally develop out of lipids that prefer to remain at the intersection of the droplet and outside liquid.

Credit: Lucy Reading-Ikkanda/Quanta Magazine
As a kind of protection for what’s within the cells, genes could’ve begun coding for these membranes. But knowing anything for sure still depends on more experiments.

So, if the very complex life on Earth could have begun from something as seemingly inconspicuous as liquid droplets, perhaps the same could be said of possible extraterrestrial life?

In any case, this research could help us understand how life as we know it started from the simplest material and how the chemical processes that made our lives possible emerged from these.

The energy and time it took for a protocell to develop into a living cell, and the living cells into more complex parts, until finally developing into an even more complex organism is baffling.

The process itself took billions of years to happen, so it’s not surprising we need some significant time to fully understand it.

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The above post is reprinted from materials provided by Sciencealert . Note: Materials may be edited for content and length.

Saturday, November 12, 2016

Four new symbols have been added to Mendeleev periodic table ( Nihonium, Moscovium, Tennesseen and Oganessiin )

As  of November 8, the periodic table, developed by Dmitry Mendeleev was officially completed four new symbols, according to press office of the International Union of Pure and Applied Chemistry (IUPAC).

As of November 8, the periodic table, developed by Dmitry Mendeleev was officially completed four new symbols, according to press office of the International Union of Pure and Applied Chemistry (IUPAC).

As informs VistaNews, researchers have said that as of Tuesday, November 8, symbol with the number 113 is Nihonium, Nh. Nihonium translated from Japanese means Land of the Rising Sun. Element 113 was discovered by Japanese researchers at RIKEN Institute in Japan.

The 115 th chemical element was named Moscovium, Mc. The name was chosen in honor of the Moscow region, where is located the Institute for Nuclear Research (JINR) in Dubna city. The 115 th element was discovered by Russian scientists from the Institute for Nuclear Research in Dubna, Moscow region, Russia, which is an international research center where these experiments were performed.

The chemical symbol with the number 117 was included in the table Mendeleev as the Tennesseen, which shows a recognition of research conducted by specialists in the research elements super-heavy at Oak Ridge National Laboratory in Tennessee, US, and the 118 th element is Oganessiin, discovered by researcher Yuri Oganessian, academician of the Academy of Sciences of Russian Federation, who helped enormously in the discovery and chemical research of this chemical symbol.



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Source: Descopera

Monday, November 7, 2016

Top 8: Looking for the elixir of immortality.


For hundreds of years, scientists, scholars and philosophers have chased the secret of the elixir of immortality, the transmutation of metals, and the discovery of the alkahest, a universal solvent. Work – and advances – in alchemy were so sought after that those dabbling in it went to great lengths to protect their secrets. Inspired by works like The Chymical Wedding of Christian Rosenkreutz, they often wrote in code, describing their experiments and ideas in secret languages that only they could read. The result is an esoteric practice, the history of which remains mysterious to this day. This article examines several aspects of alchemy and its history, and the works of men and women who chased the most fantastic scientific and mythological ideas of their day. We’ve also thrown in a selection of random tidbits for your alchemical pleasure.


The Real Nicolas Flamel
(Image: filip; Nicolas Flamel’s house in Paris)
When it comes to the world’s great alchemists, Nicolas Flamel is certainly one of the best-known names. All of which is ironic, really, as there is no historical evidence to suggest that he had anything at all to do with practicing alchemy.


The real Nicolas Flamel was born in 1330 and died in Paris in 1410. During his lifetime, he was well-known as a scribe and manuscript-seller, enjoying a comfortable life after marrying the wealthy widow Perenelle. Their fame came from their philanthropy, their dedication to the church and their commissioning of several sculptures. Their home still stands, one of the oldest stone buildings in Paris.

It wasn’t until the 17th century that Flamel’s name was linked to alchemy. During his days as a bookseller, Flamel supposedly published Livre des figures hieroglyphiques (which didn’t appear until 1612), and then spent the rest of his life chasing and – it’s said – eventually achieving immortality and the Philosopher’s Stone. Flamel’s reputation is one of the best examples of pseudepigraphy in history: the practice of publishing works falsely under the name of a historical personality.

Of the estimated 10 million words Newton left behind in papers and notebooks, around one million of them were written on alchemical research. This includes his code words for various substances: codes like “Green Dragon”, “the Net”, “Diana’s doves”, and, bizarrely, the “menstrual blood of the sordid whore”.


John Damian de Falcuis, Scotland’s Flying Alchemist
(Image: Otter; view toward Stirling Castle)
In 1500, the Scottish royal court noted a first of its kind: an alchemical laboratory set up with the blessing of King James IV. It was set behind a door in Stirling Castle that was off-limits to everyone but the alchemist – a shadowy figure named John Damian – and the king himself.

The Scotsman reports that Damian was less than admired at court, and that he earned the nickname of the “French leech” (despite being Italian) for the vast sums of money that the crown sank into his alchemical studies. He had wooed the king with talk of finding a way to create not just the Philosopher’s Stone, but the Elixir of Life. No one could say that he didn’t aim high, however. In 1507, he did – quite literally – just that.

During his studies, he became obsessed with the idea of finding a way to allow man to fly. By September 1507, his hard work and long hours had led to the completion of a pair of mechanical wings that he believed would let him take to the skies – and desperately maintain the patronage of the king.


The alchemist Damian hurled himself from the top of Stirling Castle, but didn’t so much fly as plummet. He broke his leg in the fall, but he retained the patronage of the king. James not only continued to fund his work, but financed a five-year tour of the continent.

Mary the Jewess
One of the earliest alchemical writers, Mary the Jewess lived some time between the first and third centuries. None of her actual writings survived, but her work was quoted and used extensively by her successors.

A remarkable number of practical inventions came from Mary’s work and research. She was the first to record the discovery of hydrochloric acid, and she developed ideas for some of the most important chemical apparatuses used today. As she was writing about her experiments with “divine water” (sulfuric acid) and “philosopher’s clay”, she also developed the mechanisms for distillation that we still use in chemistry today. The bain-marie, a double boiler still used in applications like the melting of chocolate and small-scale soap production, is little changed from Mary the Jewess’ invention some 2,000 years ago.

Legend says that Japan was discovered when Qin Shi Huang sent 500 men and 500 women to explore the eastern seas with the Taoist alchemist Xu Fu. They were looking for the elixir of immortality.



Cleopatra the Alchemist
Cleopatra wasn’t her real name, but she was a very real alchemist and philosopher writing in Egypt during the 3rd century. One of four female alchemists (along with Mary the Jewess) reported to have the knowledge needed to create the Philosopher’s Stone, she also created something that’s had a marked influence on our world today: the alembic still.


Cleopatra (not to be confused with the famous queen, Cleopatra VII) wrote extensively on the transformation of life and the quantification of alchemical experiments. She also coined the term “chrysopoeia”, referring to one of the most well-known alchemical concepts, the search for the method of turning base metals into gold.

Alchemy had its own set of symbols used to indicate some of the most common substances and processes. Some of those processes were linked to the signs of the zodiac; the sign for Separation and Scorpio are the same, for example, along with the sign for Digestion and Leo, and Fermentation and Capricorn.

The Alchemical Waters
(Image: Thejohnnler; aqua regia seen in a lab)

Alchemy had its own set of symbols used to indicate some of the most common substances and processes. Some of those processes were linked to the signs of the zodiac; the sign for Separation and Scorpio are the same, for example, along with the sign for Digestion and Leo, and Fermentation and Capricorn.

Alchemical experiments throughout history were incredibly varied, but one common theme that ran through the centuries was the idea of the alchemical waters. Aqua fortis (strong water) was a highly corrosive liquid that could dissolve anything except gold. It was made by combining various percentages of sand, vitriol, alum and saltpeter, then distilling the mixture.

Aqua vitae (the water of life), meanwhile, was originally made from distilling wine, and referred to water with a high concentration of ethanol. Eventually, it became forever linked with the idea of distilling liquors. The king’s water, or aqua regia, was given its name due to its ability to dissolve gold and platinum. A mixture of hydrochloric acid and nitric acid, it has also been called “royal water”.

Perhaps the strangest is aqua omnium florum, or all-flower water. The name is rather deceiving, as this alchemical ingredient was made by distilling the water removed from cow dung – specifically, dung that was gathered from the fields in May and produced by cows that ate meadow grass and wildflowers. It was mixed with white wine and snails.


The 17th century alchemist Hennig Brand took a bizarre approach to creating the Philosopher’s Stone. Believing that the key to alchemy could be found in water and in the human body, he collected huge amounts of urine and subjected the samples to various experiments. He didn’t find the mythical stone, but he did discover phosphorus.


Alchemy and Laudanum
(Image: Cydone)
Laudanum is well known as the bane of Victorian England, but its discovery dates back to the 16th century and Paracelsus. According to the story, Paracelsus was seeking to unlock the potential healing powers of opium, and discovered that opium was most soluble in alcohol. He would go on to claim that his concoction (which he called his “arcanum”), could cure all illnesses apart from leprosy. He even claimed that it could bring someone back from the dead.

The ingredients of Paracelsus’s laudanum are something of a mystery, as he only gave the recipe to those he initiated into his studies. According to some records, the recipe included opium, henbane, the bezoar stone from a cow’s intestines, musk oil, amber, crushed pearls, coral, mummy, and parts of the heart of a stag and a unicorn.


Later, Thomas Sydenham would claim to have created his own version of the medicine from Paracelsus’s original recipe, and would later be credited with its widespread use across Europe.


Belgian alchemist Jean Baptista van Helmont claimed to have seen the Philosopher’s Stone in action. He said that it was the colour of saffron and had the texture of glass, and that he had seen it turn quicksilver into gold.


Creating the Homunculus
(Images: (left, right) via Wikipedia)
The term “homunculus” was coined by the legendary alchemist and occultist Paracelsus, and the creation of the creature was the subject of numerous 16th century experiments. The basis of the experiment was similar to the creation of the folkloric golem. Numerous alchemists tried it, but we know Paracelsus’s methods.

According to De natura rerum, the process for creating a tiny person was pretty straightforward, if not a bit labour-intensive. Seal some sperm in a horse’s womb until it starts to move on its own, then remove the tiny little man. Feed it human blood for the next 40 weeks, and Paracelsus says that it’ll mature into a little human-like child.

Like-minded individuals loved the idea. It was rumoured that Count Johann von Kefstein had created 10 such beings that could predict the future, and others claimed to have created homunculus that could commune with the spirit world.

Since the writings of Galen, it was believed that the four humors were responsible for creating balance – or imbalance – in the human body. Paracelsus thought differently, writing about three humors: salt (stability), sulphur (combustibility), and mercury (liquidity).

Sir Isaac Newton & the Philosopher’s Stone

At the same time Newton was discovering the secrets of optics and astronomy, he was also searching for the Philosopher’s Stone. In his work “Humores mineralis”, he describes what he sees as mystical properties found in saltpeter, and suggests that this substance is as close to the stone as anyone has come.

The problem Newton faced, however, was over how there could be so many minerals on the surface of the earth, when the water cycle should have been draining them all away into the underground. Minerals never rose to the surface, after all, and that was a problem.

He speculated that there was some sort of reaction going on near the surface of the earth that was replenishing all of these minerals, and that saltpeter was the active ingredient. Along with mercury and sulphur, saltpeter was thought to be one of the crucial elements in the transmutation of minerals and ore – a reaction he studied in the laboratory.

Countless alchemical works were lost in 292 AD, when the Roman Emperor Diocletian ordered all magical and alchemical books to be burned. Only a relative handful of original documents survived.



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Sunday, October 9, 2016

2016 Nobel Prize in Chemistry was awarded to researchers Jean Pierre Sauvage Sir J. Fraser Stoddart and Bernard L. Feringa

Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa were rewarded with the Nobel Prize for Chemistry by the Royal Swedish Academy of Sciences jury. They were awarded for the design and synthesis of molecular machines.

Experts have developed the smallest machine in the world. 2016 Nobel laureates were honored for developing molecular machines that are currently thousands of times thinner than a human hair.

Royal Swedish Academy of Sciences has decided to award the Nobel Prize for Chemistry in 2016 by Jean-Perre Sauvage, University of Strasbourg, France, Sir J. Fraser Stoddart at Northwestern University, Evanston, IL, USA, and Bernard L. Feringa at the University of Groningen, Netherlands.


Jean-Perre Sauvage, University of Strasbourg, France, Sir J. Fraser Stoddart at Northwestern University, Evanston, IL, USA, and Bernard L. Feringa at the University of Groningen, Netherlands.
 The machine developed by Jean-Pierre Sauvage, Fraser Stoddart and Ben Feringa will be used by researchers worldwide to develop advanced creations. One of the examples is uitmitoare molecular robot that can catch and can connect amino acids, built in 2013.
Other researchers polymer molecular motors connected to form a net. When molecular motors are exposed to light, the net tightening in a bundle. If researchers will discover a light recovery technique could
develop a new type of battery.
Computational technology development demonstrates how miniaturization technology (or nanotechnology) can lead to a revolution. Nobel laureates in Chemistry 2016 have pushed so miniaturized machines and chemistry to a new dimension, says the press release published on the official website of the prestigious Nobel prizes.
The first step in designing a molecular machines was made by Jean-Pierre Sauvage in 1983, when he managed to link two ring-shaped molecules together to form a chain called "chain". Normally, the molecules are linked by strong covalent bonds, which atoms share electrons. Instead chain were connected by a mechanical link freer. A machine able to perform a task should be composed of parts that can move relative to each other. The two rings joined fulfilled this requirement exactly.
The second step was taken by Fraser Stoddart in 1991, when he developed a "rotaxane" [ "rotaxane" - an architecture molecular synchronized mechanically composed of a molecule shaped like a dumbbell that is threaded into a macrocycle molecular (a macrocycle is formed chains of 8 or more molecules, or 12 or more molecules, for example the drugs in series of macrolides, according to literature - No]. He threaded a ring molecular on a shaft molecular thin and proved that ring can move around the axis. Among the things he developed based on "rotaxane" are: a molecular elevator, a molecular muscles and a computer chip at the molecular level.
Bernard Feringa was the first person who developed a molecular motor; in 1999, he managed to make a molecular rotor blade to continuously rotate in the same direction. Using molecular motors, it has turned a glass cylinder, which is 10,000 times higher than the engine and also designed a nanomachines.
2016 Chemistry Nobel Prize laureates have brought stalemate equilibrium molecular systems causing them to move in a controlled manner. In terms of development, molecular motor is the same level that was the electric motor in the 1830s, when engineers have developed various levers and wheels, without knowing that these inventions will lead to the production of electric trains, washing machines, the fans and the machines that process food. Nanomachines (molecular machines) will most likely be used in developing new materials, sensors and energy storage systems.


 Nobel Prize in Chemistry this year was given to researchers in recognition of their success in linking molecules to design anything from a car engine at small scale muscle.
"They have mastered the movements of control molecular scale," according to Olof Ramstrom, the Nobel Committee.
Reacting to the announcement of the prize Professor Feringa said: "I do not know what to say, I'm shocked. And my second reaction was: I'm a little nervous."
Jean-Pierre Sauvage was born in 1944 in Paris, France. He obtained a doctorate in 1971 from the University of Strasbourg. Professor emeritus at the University of Strasbourg and emeritus director of research at the National Centre for Scientific Research in France.
Sir J. Fraser Stoddart was born in 1942 in Edinburgh, UK. He obtained a doctorate in 1966 from the University of Edinburgh. Part of the Administration Council of Teachers of Chemistry in Northwestern University, Evanston, USA.Bernard L. Feringa was born in 1951 in Barger-Compascuum, Netherlands. He has obtained a doctorate in 1978 from the University of Groningen, Netherlands. Is a professor in organic chemistry at the University of Groningen, Netherlands.
Jean-Pierre Sauvage, Sir Bernard J Fraser Stoddart and L Feringa will share the prize of 8 million Swedish kronor (about 850,000 euros) for the design and synthesis of molecular-scale machines.
Winners will receive one gold medal. On Medal in Chemistry Nobel laureates in Physics and it is Nature, in the form of a goddess, like Isis, coming out of the clouds and has hands horn of plenty, and the veil which covers the face austere genius is supported by Science.
On the medal is inscribed a quote from Virgil, Aeneid inspired: Inventas vitam juvat excoluisse per artes (Inventions enrich life which art adorns a), and below is engraved the name of the laureate. The design belongs to Erik Lindberg.
Nobel diploma and is a unique work of art created by the most famous artists and calligraphers Swedes and Norwegians.
In 2015, Swedish researchers Tomas Lindahl, American and Turkish-American Paul Modrich Aziz Sancar were rewarded with the Nobel Prize in Chemistry for their studies about the cellular mechanisms of DNA repair, according to the Nobel Committee motivation.
Chemistry was the importance of science in their work of Alfred Nobel, chemist, inventor and industrialist with businesses in the production of weapons. Putting his inventions and the whole industrial process from its factories were based on knowledge of chemistry and, therefore, the chemistry was the second field of the awards after physics, said the Nobel in his will.
From 1901 to 2014, there were 172 winners of the Nobel Prize for Chemistry 106 reward being awarded in the years 1916, 1917, 1919, 1924, 1933, 1940, 1941, and 1942.
Only four women have received this award: 1911 - Marie Curie (who Aprime Nobel Prize in Physics in 1903) 1935 - Irène Joliot-Curie (daughter of Marie Curie and the wife of Frédéric Joliot) 1964 - Dorothy Crowfoot Hodgkin in 2009 - Ada Yonath.
Frederick Sanger received the Nobel Prize for Chemistry twice (1958 and 1980).



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Source: Descopera

Thursday, September 22, 2016

Marie Curie - the most important women in science



Marie Curie, the first woman to win the Nobel Prize and the first scientist who won the award twice, in two different fields, physics and chemistry, was voted the leading woman scientist of all time.

Researcher of Polish origin who discovered the treatment of cancer with radiation, was passed at a rate of 25.4 percent, nearly double the second place, Rosalind Franklin, nationality English biophysicist who helped discover the structure of DNA.


The following places were occupied by astrophysicist Dame Jocelyn Bell Burnell and Dr. Jane Goodall, primatologist who brought to the attention of the scientific world primates.

Marie Curie (7 November 1867 – 4 July 1934), née Maria Salomea Skłodowska was a Polish physicist and chemist, working mainly in France,who is famous for her pioneering research on radioactivity. She was the first woman to win a Nobel Prize, the only woman to win in two fields, and the only person to win in multiple sciences. She was also the first female professor at the University of Paris (La Sorbonne), and in 1995 became the first woman to be entombed on her own merits in Paris' Panthéon.

She was born in Warsaw, in the Congress Kingdom of Poland, then part of the Russian Empire. She studied at Warsaw's clandestine Floating University and began her practical scientific training in Warsaw. In 1891, aged 24, she followed her older sister Bronisława to study in Paris, where she earned her higher degrees and conducted her subsequent scientific work. She shared her 1903 Nobel Prize in Physics with her husband Pierre Curie and with physicist Henri Becquerel. She was the sole winner of the 1911 Nobel Prize in Chemistry.

Her achievements included a theory of radioactivity (a term that the Curies coined), techniques for isolating radioactive isotopes, and the discovery of two elements, polonium and radium. Under her direction, the world's first studies were conducted into the treatment of neoplasms, using radioactive isotopes. She founded the Curie Institutes in Paris and in Warsaw, which remain major centres of medical research today. During World War I, she established the first military field radiological centres.

While a French citizen, Marie Skłodowska Curie (she used both surnames)never lost her sense of Polish identity. She taught her daughters the Polish language and took them on visits to Poland.She named the first chemical element that she discovered – polonium, which she first isolated in 1898 – after her native country.

Curie died in 1934 at the sanatorium of Sancellemoz (Haute-Savoie), France, due to aplastic anemia brought on by her years of exposure to radiation.

"The survey indicates the vital need to celebrate and draw attention to the many women researchers, who helped form what we now call modern science," said Dr. Roger Highfield, editor of The New Scientist.

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Source: The Telegraph